Medical Assistant salary in St. Louis, MO-IL

Medical Assistants in the St. Louis, MO-IL metro area earn a median of $44,710 a year ($21.50 an hour), based on BLS data for 6,170 workers.

Median salary
$44,710
Hourly
$21.50
Average
$43,730
Top 10% earn
$48,620
Workers
6,170

Pay ranges from $36,670 for the lowest-paid 10% to $48,620 for the top 10%. That is 2% lower than the national median of $45,690. Pay here is 11% higher than the Missouri statewide median of $40,440. There are 4.6 medical assistants per 1,000 jobs here — close to the national average. The average (mean) salary is $43,730, close to the median.

Pay range for medical assistants in St. Louis, MO-IL

$0$70,000
Pay levelYearlyHourly
10th percentile (entry level)$36,670$17.63
25th percentile$38,550$18.53
Median$44,710$21.50
75th percentile$47,600$22.88
90th percentile (top earners)$48,620$23.38
Average (mean)$43,730$21.02

Half of medical assistants earn more than the median and half earn less. Percentiles show the spread: 10% earn less than the 10th percentile, and 10% earn more than the 90th.

Median paycheck, before taxes

Pay periodAmount
Monthly$3,725.83
Semi-monthly (24 a year)$1,862.92
Biweekly (26 a year)$1,719.62
Weekly$859.81
Hourly$21.50

Based on a full-time year of 2,080 hours. Convert any amount with the hourly to salary converter.

Buying a home? On a $44,710 salary, see how much house you can afford in Missouri at today's mortgage rates, or work out a payment with the mortgage calculator.

Medical Assistant salary in other metro areas nearby

Metro areaMedian salaryWorkers
Chicago-Naperville-Elgin, IL-IN$47,27015,640
Kansas City, MO-KS$45,3004,220
Springfield, IL$45,140790
Davenport-Moline-Rock Island, IA-IL$44,700840
Peoria, IL$44,680710
Rockford, IL$44,390690
Decatur, IL$43,060130
Columbia, MO$41,350380
St. Joseph, MO-KS$40,280270
Paducah, KY-IL$39,360450
Champaign-Urbana, IL$39,130460
Kankakee, IL$38,440210
Jefferson City, MO$38,260280
Bloomington, IL$38,070230
Springfield, MO$37,8701,600
Cape Girardeau, MO-IL$37,470350
Joplin, MO-KS$37,220440

Highest-paying states for medical assistants

StateMedian salary
Washington$59,290
Alaska$52,560
District of Columbia$51,050
Minnesota$50,480
Oregon$50,410
California$49,660
Massachusetts$49,460
Wisconsin$48,680
Hawaii$48,410
Colorado$48,400

See Medical Assistant pay in every state or the Missouri statewide figures.

Related jobs in St. Louis, MO-IL

More: Healthcare Support Occupations · all salaries in St. Louis, MO-IL

Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025 estimates, occupation code 31-9092. Wages include base pay, tips, commissions and shift pay, but not overtime, bonuses or benefits, and exclude the self-employed.

Frequently asked questions

How much does a medical assistant make in St. Louis, MO-IL?

The median salary for medical assistants in the St. Louis, MO-IL metro area is $44,710 a year, or $21.50 an hour. Pay ranges from $36,670 for the lowest-paid 10% to $48,620 for the top 10%.

How much do the highest-paid medical assistants make in St. Louis, MO-IL?

The top 10% of medical assistants in the St. Louis, MO-IL metro area earn at least $48,620 a year. The top 25% earn $47,600 or more.

What is the starting pay for medical assistants in St. Louis, MO-IL?

Entry-level pay (the 10th percentile) is about $36,670 a year, and a quarter of medical assistants earn $38,550 or less.

How many medical assistants work in St. Louis, MO-IL?

About 6,170 medical assistants are employed in the St. Louis, MO-IL metro area, not counting the self-employed.