Medical Assistant salary in Columbia, MO

Medical Assistants in the Columbia, MO metro area earn a median of $41,350 a year ($19.88 an hour), based on BLS data for 380 workers.

Median salary
$41,350
Hourly
$19.88
Average
$41,790
Top 10% earn
$50,100
Workers
380

Pay ranges from $33,290 for the lowest-paid 10% to $50,100 for the top 10%. That is 9% lower than the national median of $45,690. Pay here is 2% higher than the Missouri statewide median of $40,440. There are 3.6 medical assistants per 1,000 jobs here — the job is less common than nationally (location quotient 0.68). The average (mean) salary is $41,790, above the median because a few high earners pull it up.

Pay range for medical assistants in Columbia, MO

$0$70,000
Pay levelYearlyHourly
10th percentile (entry level)$33,290$16.01
25th percentile$37,540$18.05
Median$41,350$19.88
75th percentile$45,540$21.90
90th percentile (top earners)$50,100$24.09
Average (mean)$41,790$20.09

Half of medical assistants earn more than the median and half earn less. Percentiles show the spread: 10% earn less than the 10th percentile, and 10% earn more than the 90th.

Median paycheck, before taxes

Pay periodAmount
Monthly$3,445.83
Semi-monthly (24 a year)$1,722.92
Biweekly (26 a year)$1,590.38
Weekly$795.19
Hourly$19.88

Based on a full-time year of 2,080 hours. Convert any amount with the hourly to salary converter.

Buying a home? On a $41,350 salary, see how much house you can afford in Missouri at today's mortgage rates, or work out a payment with the mortgage calculator.

Medical Assistant salary in other metro areas nearby

Metro areaMedian salaryWorkers
Kansas City, MO-KS$45,3004,220
St. Louis, MO-IL$44,7106,170
St. Joseph, MO-KS$40,280270
Jefferson City, MO$38,260280
Springfield, MO$37,8701,600
Cape Girardeau, MO-IL$37,470350
Joplin, MO-KS$37,220440

Highest-paying states for medical assistants

StateMedian salary
Washington$59,290
Alaska$52,560
District of Columbia$51,050
Minnesota$50,480
Oregon$50,410
California$49,660
Massachusetts$49,460
Wisconsin$48,680
Hawaii$48,410
Colorado$48,400

See Medical Assistant pay in every state or the Missouri statewide figures.

Related jobs in Columbia, MO

More: Healthcare Support Occupations · all salaries in Columbia, MO

Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025 estimates, occupation code 31-9092. Wages include base pay, tips, commissions and shift pay, but not overtime, bonuses or benefits, and exclude the self-employed.

Frequently asked questions

How much does a medical assistant make in Columbia, MO?

The median salary for medical assistants in the Columbia, MO metro area is $41,350 a year, or $19.88 an hour. Pay ranges from $33,290 for the lowest-paid 10% to $50,100 for the top 10%.

How much do the highest-paid medical assistants make in Columbia, MO?

The top 10% of medical assistants in the Columbia, MO metro area earn at least $50,100 a year. The top 25% earn $45,540 or more.

What is the starting pay for medical assistants in Columbia, MO?

Entry-level pay (the 10th percentile) is about $33,290 a year, and a quarter of medical assistants earn $37,540 or less.

How many medical assistants work in Columbia, MO?

About 380 medical assistants are employed in the Columbia, MO metro area, not counting the self-employed.