Nurse Practitioner salary in South Carolina
Nurse Practitioners in South Carolina earn a median of $123,290 a year ($59.28 an hour), based on BLS data for 5,670 workers.
Pay ranges from $97,080 for the lowest-paid 10% to $160,170 for the top 10%. That is 7% lower than the national median of $132,300. South Carolina ranks 48th of 51 states for nurse practitioners pay. There are 2.5 nurse practitioners per 1,000 jobs here — close to the national average. The average (mean) salary is $124,170, above the median because a few high earners pull it up.
Pay range for nurse practitioners in South Carolina
| Pay level | Yearly | Hourly |
|---|---|---|
| 10th percentile (entry level) | $97,080 | $46.67 |
| 25th percentile | $107,930 | $51.89 |
| Median | $123,290 | $59.28 |
| 75th percentile | $132,220 | $63.57 |
| 90th percentile (top earners) | $160,170 | $77.01 |
| Average (mean) | $124,170 | $59.70 |
Half of nurse practitioners earn more than the median and half earn less. Percentiles show the spread: 10% earn less than the 10th percentile, and 10% earn more than the 90th.
Median paycheck, before taxes
| Pay period | Amount |
|---|---|
| Monthly | $10,274.17 |
| Semi-monthly (24 a year) | $5,137.08 |
| Biweekly (26 a year) | $4,741.92 |
| Weekly | $2,370.96 |
| Hourly | $59.28 |
Based on a full-time year of 2,080 hours. Convert any amount with the hourly to salary converter.
Buying a home? On a $123,290 salary, see how much house you can afford in South Carolina at today's mortgage rates, or work out a payment with the mortgage calculator.
Nurse Practitioner salary in cities in South Carolina
| Metro area | Median salary | Workers |
|---|---|---|
| Charlotte-Concord-Gastonia, NC-SC | $130,310 | 1,970 |
| Charleston-North Charleston, SC | $127,780 | 1,050 |
| Florence, SC | $121,930 | 270 |
| Myrtle Beach-Conway-North Myrtle Beach, SC | $121,390 | 260 |
| Spartanburg, SC | $121,120 | 260 |
| Augusta-Richmond County, GA-SC | $120,270 | 500 |
| Greenville-Anderson-Greer, SC | $119,280 | 1,120 |
| Hilton Head Island-Bluffton-Port Royal, SC | $119,130 | 260 |
| Columbia, SC | $118,470 | 920 |
| Sumter, SC | $112,080 | 80 |
Highest-paying states for nurse practitioners
| State | Median salary |
|---|---|
| California | $168,520 |
| New Jersey | $159,310 |
| Washington | $156,100 |
| Oregon | $155,680 |
| Alaska | $155,170 |
| New York | $153,510 |
| Massachusetts | $142,440 |
| Nevada | $140,670 |
| Connecticut | $138,470 |
| New Hampshire | $137,550 |
Related jobs in South Carolina
| Job | Median salary | Hourly |
|---|---|---|
| Registered Nurse | $82,360 | $39.60 |
| Pharmacist | $135,700 | $65.24 |
| Physicians, All Other | $274,480 | $131.96 |
| Physical Therapist | $101,330 | $48.72 |
| Dental Hygienist | $84,340 | $40.55 |
| Physician Assistant | $122,490 | $58.89 |
| Speech-Language Pathologist | $90,530 | $43.52 |
| Dentists, General | $158,640 | $76.27 |
| Respiratory Therapist | $77,740 | $37.38 |
| Occupational Therapist | $101,130 | $48.62 |
| Veterinarian | $122,130 | $58.72 |
| General Internal Medicine Physician | $359,500 | $172.84 |
| Family Medicine Physician | $239,200 | $115.00 |
| Nurse Anesthetist | $265,480 | $127.64 |
More: Healthcare Practitioners and Technical Occupations · all salaries in South Carolina
Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025 estimates, occupation code 29-1171. Wages include base pay, tips, commissions and shift pay, but not overtime, bonuses or benefits, and exclude the self-employed.
Frequently asked questions
How much does a nurse practitioner make in South Carolina?
The median salary for nurse practitioners in South Carolina is $123,290 a year, or $59.28 an hour. Pay ranges from $97,080 for the lowest-paid 10% to $160,170 for the top 10%.
How much do the highest-paid nurse practitioners make in South Carolina?
The top 10% of nurse practitioners in South Carolina earn at least $160,170 a year. The top 25% earn $132,220 or more.
What is the starting pay for nurse practitioners in South Carolina?
Entry-level pay (the 10th percentile) is about $97,080 a year, and a quarter of nurse practitioners earn $107,930 or less.
How many nurse practitioners work in South Carolina?
About 5,670 nurse practitioners are employed in South Carolina, not counting the self-employed.