Medical Assistant salary in Columbia, SC

Medical Assistants in the Columbia, SC metro area earn a median of $40,680 a year ($19.56 an hour), based on BLS data for 2,190 workers.

Median salary
$40,680
Hourly
$19.56
Average
$41,710
Top 10% earn
$47,540
Workers
2,190

Pay ranges from $35,410 for the lowest-paid 10% to $47,540 for the top 10%. That is 11% lower than the national median of $45,690. Pay here is 1% lower than the South Carolina statewide median of $41,160. There are 5.6 medical assistants per 1,000 jobs here — close to the national average. The average (mean) salary is $41,710, above the median because a few high earners pull it up.

Pay range for medical assistants in Columbia, SC

$0$70,000
Pay levelYearlyHourly
10th percentile (entry level)$35,410$17.02
25th percentile$37,290$17.93
Median$40,680$19.56
75th percentile$45,770$22.00
90th percentile (top earners)$47,540$22.86
Average (mean)$41,710$20.05

Half of medical assistants earn more than the median and half earn less. Percentiles show the spread: 10% earn less than the 10th percentile, and 10% earn more than the 90th.

Median paycheck, before taxes

Pay periodAmount
Monthly$3,390
Semi-monthly (24 a year)$1,695
Biweekly (26 a year)$1,564.62
Weekly$782.31
Hourly$19.56

Based on a full-time year of 2,080 hours. Convert any amount with the hourly to salary converter.

Buying a home? On a $40,680 salary, see how much house you can afford in South Carolina at today's mortgage rates, or work out a payment with the mortgage calculator.

Medical Assistant salary in other metro areas nearby

Highest-paying states for medical assistants

StateMedian salary
Washington$59,290
Alaska$52,560
District of Columbia$51,050
Minnesota$50,480
Oregon$50,410
California$49,660
Massachusetts$49,460
Wisconsin$48,680
Hawaii$48,410
Colorado$48,400

See Medical Assistant pay in every state or the South Carolina statewide figures.

Related jobs in Columbia, SC

More: Healthcare Support Occupations · all salaries in Columbia, SC

Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025 estimates, occupation code 31-9092. Wages include base pay, tips, commissions and shift pay, but not overtime, bonuses or benefits, and exclude the self-employed.

Frequently asked questions

How much does a medical assistant make in Columbia, SC?

The median salary for medical assistants in the Columbia, SC metro area is $40,680 a year, or $19.56 an hour. Pay ranges from $35,410 for the lowest-paid 10% to $47,540 for the top 10%.

How much do the highest-paid medical assistants make in Columbia, SC?

The top 10% of medical assistants in the Columbia, SC metro area earn at least $47,540 a year. The top 25% earn $45,770 or more.

What is the starting pay for medical assistants in Columbia, SC?

Entry-level pay (the 10th percentile) is about $35,410 a year, and a quarter of medical assistants earn $37,290 or less.

How many medical assistants work in Columbia, SC?

About 2,190 medical assistants are employed in the Columbia, SC metro area, not counting the self-employed.